منابع مشابه
Chromosomes of human endometrium.
Evidence is gradually accumulating about acquired somatic chromosome anomalies, particularly those of neoplasms. Unfortunately, control observations are almost entirely lacking. It is generally assumed that all the tissues of the body consist of cells with the normal karyotype as it is seen in cultured lymphocytes or fibroblasts, but this has not yet been shown to be the case. Even bone-marrow,...
متن کاملRing chromosomes in human neoplasias.
Though reported from a wide variety of human neoplasias, ring chromosomes, in general, are a rare finding in these diseases. The majority were detected by chance when tumors were screened for chromosomal aberrations. In most cases they are a part of highly complex karyotypic alterations and therefore part of unfavourable prognostic factors. However, in some tumor entities (e.g. tumors of mesenc...
متن کاملChromosomes of human cancer cells.
Obvious mitotic abnormalities have long been known to occur very commonly in malignant tumours, but as a result of recent improvements in technique much more reliable cytogenetic observations are now possible. Transplantable tumours were the first to be accurately examined, and these were found to consist of populations of cells with variations around a modal (" stemline ") type which differs i...
متن کاملInternal ultrastructure of human chromosomes.
By preparing metaphase chromosome spreads on Aclar (polychlorotrifluoroethylene fluoropolymer) film and incorporating a conventional karyotyping system, it was possible to observe the internal ultrastructure of individual chromosomes with known karyotype by means of transmission electron microscopy. Essentially, all 46 chromosomes per human cell could be examined. Application of this method to ...
متن کاملSpecific banding patterns of human chromosomes.
Individual pairs of human chromosomes can be reliably identified by a new method that does not require special optical equipment and that results in permanent preparations. This method, which is based on treatment of the chromosomes in situ with NaOH, followed by incubation in sodium chloride-trisodium citrate and Giemsa staining, results in highly specific banding patterns in characteristic re...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 1974
ISSN: 1468-6244
DOI: 10.1136/jmg.11.3.315-a